NANOG initiates epiblast fate through the coordination of pluripotency genes expression
NANOG initiates epiblast fate through the coordination of pluripotency genes expression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The epiblast is the source of all mammalian embryonic tissues and of pluripotent embryonic stem cells. It differentiates alongside the primitive endoderm in a “salt and pepper” pattern from inner cell mass (ICM) progenitors during the preimplantation stages through the activity of NANOG, GATA6 and the FGF pathway. When and how epiblast lineage spec...
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NANOG initiates epiblast fate through the coordination of pluripotency genes expression
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TN_cdi_doaj_primary_oai_doaj_org_article_68754255ea774c4fb0569f082cd82c5f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_68754255ea774c4fb0569f082cd82c5f
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2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30858-8