FMNL formins boost lamellipodial force generation
FMNL formins boost lamellipodial force generation
About this item
Full title
Author / Creator
Kage, Frieda , Winterhoff, Moritz , Dimchev, Vanessa , Mueller, Jan , Thalheim, Tobias , Freise, Anika , Brühmann, Stefan , Kollasser, Jana , Block, Jennifer , Dimchev, Georgi , Geyer, Matthias , Schnittler, Hans-Joachim , Brakebusch, Cord , Stradal, Theresia E. B. , Carlier, Marie-France , Sixt, Michael , Käs, Josef , Faix, Jan and Rottner, Klemens
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Migration frequently involves Rac-mediated protrusion of lamellipodia, formed by Arp2/3 complex-dependent branching thought to be crucial for force generation and stability of these networks. The formins FMNL2 and FMNL3 are Cdc42 effectors targeting to the lamellipodium tip and shown here to nucleate and elongate actin filaments with complementary...
Alternative Titles
Full title
FMNL formins boost lamellipodial force generation
Authors, Artists and Contributors
Author / Creator
Winterhoff, Moritz
Dimchev, Vanessa
Mueller, Jan
Thalheim, Tobias
Freise, Anika
Brühmann, Stefan
Kollasser, Jana
Block, Jennifer
Dimchev, Georgi
Geyer, Matthias
Schnittler, Hans-Joachim
Brakebusch, Cord
Stradal, Theresia E. B.
Carlier, Marie-France
Sixt, Michael
Käs, Josef
Faix, Jan
Rottner, Klemens
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_68b36f54d59e40399f6718c304c31181
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_68b36f54d59e40399f6718c304c31181
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14832
