Nicotinamide mononucleotide combined with PJ-34 protects microglial cells from lipopolysaccharide-in...
Nicotinamide mononucleotide combined with PJ-34 protects microglial cells from lipopolysaccharide-induced mitochondrial impairment through NMNAT3-PARP1 axis
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Author / Creator
Li, Jia , Cheng, Xiao-Yu , Ma, Rui-Xia , Zou, Bin , Zhang, Yue , Wu, Miao-Miao , Yao, Yao and Li, Juan
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Lipopolysaccharide (LPS) is known to induce cell injury and mitochondrial dysfunction, which are pivotal in neuroinflammation and related disorders. Recent studies have demonstrated the potential of nicotinamide mononucleotide (NMN) and poly(ADP-ribose) polymerase-1 (PARP1) inhibitors to enhance mitochondrial function. However, the underlying mecha...
Alternative Titles
Full title
Nicotinamide mononucleotide combined with PJ-34 protects microglial cells from lipopolysaccharide-induced mitochondrial impairment through NMNAT3-PARP1 axis
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_69004c50918b4ddda27a3ac3bc0dd1c4
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69004c50918b4ddda27a3ac3bc0dd1c4
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-025-06280-1
