Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson...
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson’s disease
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Author / Creator
Dong, Hongtian , Zhang, Xiaoshuang , Duan, Yufei , He, Yongtao , Zhao, Jiayin , Wang, Zishan , Wang, Jinghui , Li, Qing , Fan, Guangchun , Liu, Zhaolin , Shen, Chenye , Zhang, Yunhe , Yu, Mei , Fei, Jian and Huang, Fang
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Neuroinflammation is one of the core pathological features of Parkinson’s disease (PD). Innate immune cells play a crucial role in the progression of PD. Microglia, the major innate immune cells in the brain, exhibit innate immune memory effects and are recognized as key regulators of neuroinflammatory responses. Persistent modifications of microgl...
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Full title
Hypoxia inducible factor-1α regulates microglial innate immune memory and the pathology of Parkinson’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_692770e9e37a4b48abf7bca96bf7c00d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_692770e9e37a4b48abf7bca96bf7c00d
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-024-03070-2