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Loss of ninein interferes with osteoclast formation and causes premature ossification

Loss of ninein interferes with osteoclast formation and causes premature ossification

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_694029e2d3934081838b59202a53d110

Loss of ninein interferes with osteoclast formation and causes premature ossification

About this item

Full title

Loss of ninein interferes with osteoclast formation and causes premature ossification

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2024-06, Vol.13

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Ninein is a centrosome protein that has been implicated in microtubule anchorage and centrosome cohesion. Mutations in the human
NINEIN
gene have been linked to Seckel syndrome and to a rare form of skeletal dysplasia. However, the role of ninein in skeletal development remains unknown. Here, we describe a ninein knockout mouse with advanced...

Alternative Titles

Full title

Loss of ninein interferes with osteoclast formation and causes premature ossification

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_694029e2d3934081838b59202a53d110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_694029e2d3934081838b59202a53d110

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.93457

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