Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire...
Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Next generation sequencing has allowed the discovery of miRNA isoforms, termed isomiRs. Some isomiRs are derived from imprecise processing of pre-miRNA precursors, leading to length variants. Additional variability is introduced by non-templated addition of bases at the ends or editing of internal bases, resulting in base differences relative to th...
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Paired-end small RNA sequencing reveals a possible overestimation in the isomiR sequence repertoire previously reported from conventional single read data analysis
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TN_cdi_doaj_primary_oai_doaj_org_article_6943c4994f754155964bea38112780d5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6943c4994f754155964bea38112780d5
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ISSN
1471-2105
E-ISSN
1471-2105
DOI
10.1186/s12859-021-04128-1
