The primary somatosensory sensory cortex-basolateral amygdala pathway contributes to comorbid depres...
The primary somatosensory sensory cortex-basolateral amygdala pathway contributes to comorbid depression in spared nerve injury-induced neuropathic pain
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Author / Creator
Chen, Guo , Luo, Min , Chen, Wentao , Zhang, Yu , Gu, Zuchao , Xu, Miaomiao , Zhang, Ying and Bian, Jiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Comorbid depression in chronic pain is a prevalent health problem, yet the underlying neural mechanisms remain largely unexplored. This study identified a dedicated neural circuit connecting the hind limb region of the primary somatosensory cortex (S1HL) to the basolateral amygdala (BLA) that mediated neuropathic pain-induced depression. We demonst...
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Full title
The primary somatosensory sensory cortex-basolateral amygdala pathway contributes to comorbid depression in spared nerve injury-induced neuropathic pain
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TN_cdi_doaj_primary_oai_doaj_org_article_694f5cfd6a1b4ba093507bb3be469f65
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_694f5cfd6a1b4ba093507bb3be469f65
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-97164-3
