Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Immunotherapy has only limited efficacy against pancreatic ductal adenocarcinoma (PDAC) due to the presence of an immunosuppressive tumor-associated stroma. Here, we demonstrate an effective modulation of that stroma by irreversible electroporation (IRE), a local ablation technique that has received regulatory approval in the United States. IRE ind...
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Full title
Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_6997acb67b654db0a21d5b14ff520bda
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6997acb67b654db0a21d5b14ff520bda
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-08782-1
