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Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat die...

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat die...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69dd93baf3cc42269d69f72c7d7939c7

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

About this item

Full title

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2024-05, Vol.7 (1), p.632-15, Article 632

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The stomach-derived hormone ghrelin regulates essential physiological functions. The ghrelin receptor (GHSR) has ligand-independent actions; therefore,
GHSR
gene deletion may be a reasonable approach to investigate the role of this system in feeding behaviors and diet-induced obesity (DIO). Here, we investigate the effects of a long-term (12-...

Alternative Titles

Full title

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_69dd93baf3cc42269d69f72c7d7939c7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_69dd93baf3cc42269d69f72c7d7939c7

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-06303-5

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