Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targe...
Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
About this item
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Author / Creator
Liu, Xianglan , Hu, Jiaming , Wu, Jiarui , Tian, Yiru , Wang, Jinbo , Wu, Chunyan , Chen, Qingfeng , Krall, Leonard , He, Yanping and Lu, Qun
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Human norovirus (HNV) is the predominant pathogen causing outbreaks of acute gastroenteritis globally. Despite significant efforts to combat norovirus infections, there is currently no FDA approved vaccine or antiviral drug available. Consequently, the development of effective antiviral agents is of critical importance.
In this study, a series o...
Alternative Titles
Full title
Identification of Co-29, a 5-cyano-2-thiacetyl aromatic pyrimidinone, as a potential inhibitor targeting the RdRp of norovirus
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6a35cad615a6428d9886b2f498dd3c1a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a35cad615a6428d9886b2f498dd3c1a
Other Identifiers
ISSN
1743-422X
E-ISSN
1743-422X
DOI
10.1186/s12985-025-02687-w
