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Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibo...

Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a3b4e7e0e904e558051fa10c7c7f475

Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod

About this item

Full title

Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod

Publisher

London: BioMed Central Ltd

Journal title

Journal of neuroinflammation, 2020-07, Vol.17 (1), p.1-206, Article 206

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS). Japanese MS patients treated with fingolimod were reported to be 10 times more likely to develop PML than equivalent patients in other countries. The strongest...

Alternative Titles

Full title

Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6a3b4e7e0e904e558051fa10c7c7f475

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a3b4e7e0e904e558051fa10c7c7f475

Other Identifiers

ISSN

1742-2094

E-ISSN

1742-2094

DOI

10.1186/s12974-020-01865-7

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