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GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate...

GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a55ab8d84e5441b8d4eb92811819642

GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation

About this item

Full title

GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation

Publisher

United States: John Wiley & Sons, Inc

Journal title

Physiological Reports, 2022-08, Vol.10 (15), p.e15415-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Left ventricular diastolic dysfunction is a structural and functional condition that precedes the development of heart failure with preserved ejection fraction (HFpEF). The etiology of diastolic dysfunction includes alterations in fuel substrate metabolism that negatively impact cardiac bioenergetics, and may precipitate the eventual transition to...

Alternative Titles

Full title

GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6a55ab8d84e5441b8d4eb92811819642

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a55ab8d84e5441b8d4eb92811819642

Other Identifiers

E-ISSN

2051-817X

DOI

10.14814/phy2.15415

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