GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate...
GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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Left ventricular diastolic dysfunction is a structural and functional condition that precedes the development of heart failure with preserved ejection fraction (HFpEF). The etiology of diastolic dysfunction includes alterations in fuel substrate metabolism that negatively impact cardiac bioenergetics, and may precipitate the eventual transition to...
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GCN5L1 impairs diastolic function in mice exposed to a high fat diet by restricting cardiac pyruvate oxidation
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TN_cdi_doaj_primary_oai_doaj_org_article_6a55ab8d84e5441b8d4eb92811819642
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a55ab8d84e5441b8d4eb92811819642
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E-ISSN
2051-817X
DOI
10.14814/phy2.15415