First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1...
First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors
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Full title
Author / Creator
Wermke, Martin , Holderried, Tobias A W , Luke, Jason John , Morris, Van K , Alsdorf, Winfried H , Wetzko, Katrin , Andersson, Borje S , Wistuba, Ignacio I , Parra, Edwin R , Hossain, Mohammad B , Grund-Gröschke, Sandra , Aslan, Katrin , Satelli, Arun , Marisetty, Anantha , Satam, Swapna , Kalra, Mamta , Hukelmann, Jens , Kursunel, M Alper , Pozo, Karine , Acs, Andreas , Backert, Linus , Baumeister, Melissa , Bunk, Sebastian , Wagner, Claudia , Schoor, Oliver , Mohamed, Ali S , Mayer-Mokler, Andrea , Hilf, Norbert , Krishna, Delfi , Walter, Steffen , Tsimberidou, Apostolia M and Britten, Cedrik M
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
Rationale of the trialAlthough the use of engineered T cells in cancer immunotherapy has greatly advanced the treatment of hematological malignancies, reaching meaningful clinical responses in the treatment of solid tumors is still challenging. We investigated the safety and tolerability of IMA202 in a first-in-human, dose escalation basket trial i...
Alternative Titles
Full title
First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors
Authors, Artists and Contributors
Author / Creator
Holderried, Tobias A W
Luke, Jason John
Morris, Van K
Alsdorf, Winfried H
Wetzko, Katrin
Andersson, Borje S
Wistuba, Ignacio I
Parra, Edwin R
Hossain, Mohammad B
Grund-Gröschke, Sandra
Aslan, Katrin
Satelli, Arun
Marisetty, Anantha
Satam, Swapna
Kalra, Mamta
Hukelmann, Jens
Kursunel, M Alper
Pozo, Karine
Acs, Andreas
Backert, Linus
Baumeister, Melissa
Bunk, Sebastian
Wagner, Claudia
Schoor, Oliver
Mohamed, Ali S
Mayer-Mokler, Andrea
Hilf, Norbert
Krishna, Delfi
Walter, Steffen
Tsimberidou, Apostolia M
Britten, Cedrik M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6a562891133f4ee084b42c34b2d77b3e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a562891133f4ee084b42c34b2d77b3e
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2023-008668
