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Structural basis of ligand binding modes at the human formyl peptide receptor 2

Structural basis of ligand binding modes at the human formyl peptide receptor 2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a6c3a3f8432461e92e7060e4f1bd1bd

Structural basis of ligand binding modes at the human formyl peptide receptor 2

About this item

Full title

Structural basis of ligand binding modes at the human formyl peptide receptor 2

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-03, Vol.11 (1), p.1208-9, Article 1208

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The human formyl peptide receptor 2 (FPR2) plays a crucial role in host defense and inflammation, and has been considered as a drug target for chronic inflammatory diseases. A variety of peptides with different structures and origins have been characterized as FPR2 ligands. However, the ligand-binding modes of FPR2 remain elusive, thereby limiting...

Alternative Titles

Full title

Structural basis of ligand binding modes at the human formyl peptide receptor 2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6a6c3a3f8432461e92e7060e4f1bd1bd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a6c3a3f8432461e92e7060e4f1bd1bd

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15009-1

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