Structural basis of ligand binding modes at the human formyl peptide receptor 2
Structural basis of ligand binding modes at the human formyl peptide receptor 2
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Chen, Tong , Xiong, Muya , Zong, Xin , Ge, Yunjun , Zhang, Hui , Wang, Mu , Won Han, Gye , Yi, Cuiying , Ma, Limin , Ye, Richard D. , Xu, Yechun , Zhao, Qiang and Wu, Beili
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The human formyl peptide receptor 2 (FPR2) plays a crucial role in host defense and inflammation, and has been considered as a drug target for chronic inflammatory diseases. A variety of peptides with different structures and origins have been characterized as FPR2 ligands. However, the ligand-binding modes of FPR2 remain elusive, thereby limiting...
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Structural basis of ligand binding modes at the human formyl peptide receptor 2
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TN_cdi_doaj_primary_oai_doaj_org_article_6a6c3a3f8432461e92e7060e4f1bd1bd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a6c3a3f8432461e92e7060e4f1bd1bd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15009-1