Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblasti...
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
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Author / Creator
Vijayakrishnan, Jayaram , Studd, James , Broderick, Peter , Kinnersley, Ben , Holroyd, Amy , Law, Philip J. , Kumar, Rajiv , Allan, James M. , Harrison, Christine J. , Moorman, Anthony V. , Vora, Ajay , Roman, Eve , Rachakonda, Sivaramakrishna , Kinsey, Sally E. , Sheridan, Eamonn , Thompson, Pamela D. , Irving, Julie A. , Koehler, Rolf , Hoffmann, Per , Nöthen, Markus M. , Heilmann-Heimbach, Stefanie , Jöckel, Karl-Heinz , Easton, Douglas F. , Pharaoh, Paul D. P. , Dunning, Alison M. , Peto, Julian , Canzian, Frederico , Swerdlow, Anthony , Eeles, Rosalind A. , Kote-Jarai, ZSofia , Muir, Kenneth , Pashayan, Nora , Greaves, Mel , Zimmerman, Martin , Bartram, Claus R. , Schrappe, Martin , Stanulla, Martin , Hemminki, Kari , Houlston, Richard S. , The PRACTICAL Consortium , PRACTICAL Consortium , PRACTICAL consortium , Faculty of Medicine , Medicinska fakulteten , Strategiska forskningsområden (SFO) , EpiHealth: Epidemiology for Health , Institutionen för kliniska vetenskaper, Malmö , Strategic research areas (SRA) , Lunds universitet , Family Medicine and Clinical Epidemiology , Profilområden och andra starka forskningsmiljöer , Lund University , Allmänmedicin och klinisk epidemiologi , Profile areas and other strong research environments and Department of Clinical Sciences, Malmö
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic leukemia (BCP-ALL); however, much of the heritable risk remains unidentified. Here, we perform a GWAS and conduct a meta-analysis with two existing GWAS, totaling 2442 cases and 14,609 controls. We identify risk loci for...
Alternative Titles
Full title
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
Authors, Artists and Contributors
Author / Creator
Studd, James
Broderick, Peter
Kinnersley, Ben
Holroyd, Amy
Law, Philip J.
Kumar, Rajiv
Allan, James M.
Harrison, Christine J.
Moorman, Anthony V.
Vora, Ajay
Roman, Eve
Rachakonda, Sivaramakrishna
Kinsey, Sally E.
Sheridan, Eamonn
Thompson, Pamela D.
Irving, Julie A.
Koehler, Rolf
Hoffmann, Per
Nöthen, Markus M.
Heilmann-Heimbach, Stefanie
Jöckel, Karl-Heinz
Easton, Douglas F.
Pharaoh, Paul D. P.
Dunning, Alison M.
Peto, Julian
Canzian, Frederico
Swerdlow, Anthony
Eeles, Rosalind A.
Kote-Jarai, ZSofia
Muir, Kenneth
Pashayan, Nora
Greaves, Mel
Zimmerman, Martin
Bartram, Claus R.
Schrappe, Martin
Stanulla, Martin
Hemminki, Kari
Houlston, Richard S.
The PRACTICAL Consortium
PRACTICAL Consortium
PRACTICAL consortium
Faculty of Medicine
Medicinska fakulteten
Strategiska forskningsområden (SFO)
EpiHealth: Epidemiology for Health
Institutionen för kliniska vetenskaper, Malmö
Strategic research areas (SRA)
Lunds universitet
Family Medicine and Clinical Epidemiology
Profilområden och andra starka forskningsmiljöer
Lund University
Allmänmedicin och klinisk epidemiologi
Profile areas and other strong research environments
Department of Clinical Sciences, Malmö
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6a850276ab0d4ba1a6215db9280b774f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6a850276ab0d4ba1a6215db9280b774f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03178-z
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