Activation of cryptic splice sites in three patients with chronic granulomatous disease
Activation of cryptic splice sites in three patients with chronic granulomatous disease
About this item
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Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
Background
Chronic granulomatous disease (CGD) is a primary immune deficiency caused by mutations in the genes encoding the structural components of the phagocyte NADPH oxidase. As a result, the patients cannot generate sufficient amounts of reactive oxygen species required for killing pathogenic microorganisms.
Methods
We analyzed NADPH o...
Alternative Titles
Full title
Activation of cryptic splice sites in three patients with chronic granulomatous disease
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TN_cdi_doaj_primary_oai_doaj_org_article_6aaafce9ab32417c8a5bcf17397ff9b5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6aaafce9ab32417c8a5bcf17397ff9b5
Other Identifiers
ISSN
2324-9269
E-ISSN
2324-9269
DOI
10.1002/mgg3.854
