Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases
Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Future therapeutic use of engineered site-directed nucleases, like zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs), relies on safe and effective means of delivering nucleases to cells. In this study, we adapt lentiviral vectors as carriers of designer nuclease proteins, providing efficient targeted gene dis...
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Full title
Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases
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TN_cdi_doaj_primary_oai_doaj_org_article_6ad9332bf8e14ca1955b2edca9dd2a89
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ad9332bf8e14ca1955b2edca9dd2a89
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.01911
