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The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The...

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ae2ac770cb94708ba7339cc8b00d15d

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics

About this item

Full title

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics

Publisher

Switzerland: MDPI AG

Journal title

Metabolites, 2023-05, Vol.13 (5), p.661

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

In toxicogenetics, an integrative approach including the prediction of phenotype based on post-mortem genotyping of drug-metabolising enzymes might help explain the cause of death (CoD) and manner of death (MoD). The use of concomitant drugs, however, might lead to phenoconversion, a mismatch between the phenotype based on the genotype and the meta...

Alternative Titles

Full title

The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6ae2ac770cb94708ba7339cc8b00d15d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ae2ac770cb94708ba7339cc8b00d15d

Other Identifiers

ISSN

2218-1989

E-ISSN

2218-1989

DOI

10.3390/metabo13050661

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