The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The...
The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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In toxicogenetics, an integrative approach including the prediction of phenotype based on post-mortem genotyping of drug-metabolising enzymes might help explain the cause of death (CoD) and manner of death (MoD). The use of concomitant drugs, however, might lead to phenoconversion, a mismatch between the phenotype based on the genotype and the meta...
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Full title
The Evaluation of CYP2D6, CYP2C9, CYP2C19 , and CYP2B6 Phenoconversion in Post-Mortem Casework: The Challenge of Forensic Toxicogenetics
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TN_cdi_doaj_primary_oai_doaj_org_article_6ae2ac770cb94708ba7339cc8b00d15d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ae2ac770cb94708ba7339cc8b00d15d
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ISSN
2218-1989
E-ISSN
2218-1989
DOI
10.3390/metabo13050661