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Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian a...

Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b40637b5dc84d4c8a686f5c61ecafd7

Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells

About this item

Full title

Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2017-03, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Mechanotransducer channels at the tips of sensory stereocilia of inner ear hair cells are gated by the tension of 'tip links' interconnecting stereocilia. To ensure maximal sensitivity, tip links are tensioned at rest, resulting in a continuous influx of Ca
into the cell. Here, we show that this constitutive Ca
influx, usually considered as p...

Alternative Titles

Full title

Mechanotransduction current is essential for stability of the transducing stereocilia in mammalian auditory hair cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6b40637b5dc84d4c8a686f5c61ecafd7

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b40637b5dc84d4c8a686f5c61ecafd7

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.24661

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