Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parv...
Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised male mice
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cryptosporidium parvum
and
C. hominis
are parasites that cause life-threatening diarrhea in children and immunocompromised people. There is only one approved treatment that is modestly effective for children and ineffective for AIDS patients. Here, screening 278 compounds from the Merck KGaA, Darmstadt, Germany collection and accelerated f...
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Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised male mice
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TN_cdi_doaj_primary_oai_doaj_org_article_6b4fad2455a041379399a6eb6ce3f02b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b4fad2455a041379399a6eb6ce3f02b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52658-y
