Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection...
Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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It is necessary to develop an understanding of the specific mechanisms involved in alpha-synuclein aggregation and propagation to develop disease modifying therapies for age-related synucleinopathies, including Parkinson's disease and Dementia with Lewy Bodies. To adequately address this question, we developed a new transgenic mouse model of synucl...
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Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy
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TN_cdi_doaj_primary_oai_doaj_org_article_6b5adfc66b214f258b9f18ae019b793d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b5adfc66b214f258b9f18ae019b793d
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-020-01026-0
