Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETos...
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma
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Author / Creator
Dai, Weiwei , Tian, Ruotong , Yu, Liubing , Bian, Shasha , Chen, Yuling , Yin, Bowen , Luan, Yuxuan , Chen, Siqi , Fan, Zhuoyang , Yan, Rucheng , Pan, Xin , Hou, Yingyong , Li, Rong , Chen, Juxiang and Shu, Minfeng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Oncolytic virotherapy holds promise for cancer treatment, but the factors determining its oncolytic activity remain unclear. Neutrophil extracellular traps (NETs) are associated with cancer progression, yet their formation mechanism and role in oncolytic virotherapy remain elusive. In this study, we demonstrate that, in glioma, upregulation of IGF2...
Alternative Titles
Full title
Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma
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TN_cdi_doaj_primary_oai_doaj_org_article_6b5e47a3450741aab2f364d93eacec2a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b5e47a3450741aab2f364d93eacec2a
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44576-2
