Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal steno...
Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Lumbar spinal canal stenosis (LSS) or mechanical compression of dorsal root ganglion (DRG) is one of the causes of low back pain and neuropathic pain (NP). Lysophosphatidic acid (LPA) is a potent bioactive lipid mediator that is produced mainly from lysophosphatidylcholine (LPC) via autotaxin (ATX) and is known to induce NP via LPA
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Full title
Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis
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TN_cdi_doaj_primary_oai_doaj_org_article_6b88f183c5dc48c3a8dfbb407525812e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b88f183c5dc48c3a8dfbb407525812e
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-83569-3
