Chelator impact: investigating the pharmacokinetic behavior of copper-64 labeled PD-L1 radioligands
Chelator impact: investigating the pharmacokinetic behavior of copper-64 labeled PD-L1 radioligands
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publisher
Cham: Springer International Publishing
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Background
Programmed cell death ligand 1 (PD-L1) plays a critical role in the tumor microenvironment and overexpression in several solid cancers has been reported. This was associated with a downregulation of the local immune response, specifically of T-cells. Immune checkpoint inhibitors showed a potential to break this localized immune paraly...
Alternative Titles
Full title
Chelator impact: investigating the pharmacokinetic behavior of copper-64 labeled PD-L1 radioligands
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6b92fb27767c475693a3d55f22417df7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6b92fb27767c475693a3d55f22417df7
Other Identifiers
ISSN
2365-421X
E-ISSN
2365-421X
DOI
10.1186/s41181-024-00243-5
