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ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colore...

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colore...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6bd0e9b7df514ef89d5f3482c1a7d336

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer

About this item

Full title

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2025-04, Vol.24 (1), p.116-20, Article 116

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Colorectal cancer (CRC) is considered the third most common type of cancer worldwide. Tumor-associated macrophages (TAMs) have been shown to promote drug resistance. Adenosine-to-inosine RNA-editing, as regulated by adenosine deaminase acting on RNA (ADAR), is a process that induces the posttranscriptional modification of critical oncogenes. The ai...

Alternative Titles

Full title

ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6bd0e9b7df514ef89d5f3482c1a7d336

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6bd0e9b7df514ef89d5f3482c1a7d336

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-025-02312-y

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