Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity
Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Tau is an intracellular protein that plays a crucial role in stabilizing microtubules. However, it can aggregate into various forms under pathological conditions and be secreted into the brain parenchyma. While the consequences of tau aggregation within neurons have been extensively studied, the effects of extracellular paired helical filaments of...
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Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity
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TN_cdi_doaj_primary_oai_doaj_org_article_6c1f7d2143e94aa7af6cad42fe4dbaf4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c1f7d2143e94aa7af6cad42fe4dbaf4
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ISSN
2047-9158
E-ISSN
2047-9158
DOI
10.1186/s40035-025-00474-9
