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The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress respons...

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress respons...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c28ffb93b134c4a9132ccf90762f1c1

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

About this item

Full title

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

Publisher

England: BioMed Central Ltd

Journal title

BMC medicine, 2020-11, Vol.18 (1), p.343-22, Article 343

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Duchenne muscular dystrophy (DMD) is a progressive, degenerative muscular disorder and cognitive dysfunction caused by mutations in the dystrophin gene. It is characterized by excess inflammatory responses in the muscle and repeated degeneration and regeneration cycles. Neutral sphingomyelinase 2/sphingomyelin phosphodiesterase 3 (nSMase2/Smpd3) hy...

Alternative Titles

Full title

The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6c28ffb93b134c4a9132ccf90762f1c1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c28ffb93b134c4a9132ccf90762f1c1

Other Identifiers

ISSN

1741-7015

E-ISSN

1741-7015

DOI

10.1186/s12916-020-01805-5

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