Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; peer...
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; peer review: 2 approved]
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Publisher
England: Faculty of 1000 Ltd
Journal title
Language
English
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Publisher
England: Faculty of 1000 Ltd
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Contents
Inflammasomes are high-molecular-weight protein complexes that are formed in the cytosolic compartment in response to danger- or pathogen-associated molecular patterns. These complexes enable activation of an inflammatory protease caspase-1, leading to a cell death process called pyroptosis and to proteolytic cleavage and release of pro-inflammator...
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Full title
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; peer review: 2 approved]
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TN_cdi_doaj_primary_oai_doaj_org_article_6c3ce3c7c178442fa8b4f5fc17b2374b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c3ce3c7c178442fa8b4f5fc17b2374b
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ISSN
2046-1402
E-ISSN
2046-1402
DOI
10.12688/f1000research.8614.1
