Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation
Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation
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Author / Creator
He, Lian , Zhang, Yuanwei , Ma, Guolin , Tan, Peng , Li, Zhanjun , Zang, Shengbing , Wu, Xiang , Jing, Ji , Fang, Shaohai , Zhou, Lijuan , Wang, Youjun , Huang, Yun , Hogan, Patrick G , Han, Gang and Zhou, Yubin
Publisher
Cambridge: eLife Sciences Publications Ltd
Journal title
Language
English
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Publisher
Cambridge: eLife Sciences Publications Ltd
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Contents
The application of current channelrhodopsin-based optogenetic tools is limited by the lack of strict ion selectivity and the inability to extend the spectra sensitivity into the near-infrared (NIR) tissue transmissible range. Here we present an NIR-stimulable optogenetic platform (termed 'Opto-CRAC') that selectively and remotely controls Ca2+ osci...
Alternative Titles
Full title
Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6c4557de7dbc463bb553e26a229873c0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c4557de7dbc463bb553e26a229873c0
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.10024
