Myopathy reversion in mice after restauration of mitochondrial complex I
Myopathy reversion in mice after restauration of mitochondrial complex I
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Myopathies are common manifestations of mitochondrial diseases. To investigate whether gene replacement can be used as an effective strategy to treat or cure mitochondrial myopathies, we have generated a complex I conditional knockout mouse model lacking NDUFS3 subunit in skeletal muscle. NDUFS3 protein levels were undetectable in muscle of 15‐day‐...
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Full title
Myopathy reversion in mice after restauration of mitochondrial complex I
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TN_cdi_doaj_primary_oai_doaj_org_article_6c69102eb710425295939e5f7c462f83
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c69102eb710425295939e5f7c462f83
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201910674
