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Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neura...

Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neura...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c8c1651a3bf4c37b51d4600ee824ba6

Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs

About this item

Full title

Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-07, Vol.11 (1), p.13802-13802, Article 13802

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

ZFP57 is required to maintain the germline-marked differential methylation at imprinting control regions (ICRs) in mouse embryonic stem cells (ESCs). Although DNA methylation has a key role in genomic imprinting, several imprinted genes are controlled by different mechanisms, and a comprehensive study of the relationship between DMR methylation and...

Alternative Titles

Full title

Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6c8c1651a3bf4c37b51d4600ee824ba6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c8c1651a3bf4c37b51d4600ee824ba6

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-93297-3

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