Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neura...
Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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ZFP57 is required to maintain the germline-marked differential methylation at imprinting control regions (ICRs) in mouse embryonic stem cells (ESCs). Although DNA methylation has a key role in genomic imprinting, several imprinted genes are controlled by different mechanisms, and a comprehensive study of the relationship between DMR methylation and...
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Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs
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TN_cdi_doaj_primary_oai_doaj_org_article_6c8c1651a3bf4c37b51d4600ee824ba6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c8c1651a3bf4c37b51d4600ee824ba6
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2045-2322
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2045-2322
DOI
10.1038/s41598-021-93297-3