Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Here we report a rational strategy to orthogonally control assembly and disassembly of DNA-based nanostructures using specific IgG antibodies as molecular inputs. We first demonstrate that the binding of a specific antibody to a pair of antigen-conjugated split DNA input-strands induces their co-localization and reconstitution into a functional uni...
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Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
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TN_cdi_doaj_primary_oai_doaj_org_article_6c8c61869e6448d898aa9a1560a5556a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c8c61869e6448d898aa9a1560a5556a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13104-6
