The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc i...
The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice
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England: BioMed Central
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English
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England: BioMed Central
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Intestinal tumorigenesis is promoted by myeloid differentiation primary response gene 88 (MyD88) activation in response to the components of microbiota in Apc
mice. Microbiota also contains double-stranded RNA (dsRNA), a ligand for TLR3, which activates the toll-like receptor adaptor molecule 1 (TICAM-1, also known as TRIF) pathway.
We establ...
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The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice
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TN_cdi_doaj_primary_oai_doaj_org_article_6c9f8f8b70c44fa89f5cf60678000e7f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6c9f8f8b70c44fa89f5cf60678000e7f
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ISSN
1423-0127,1021-7770
E-ISSN
1423-0127
DOI
10.1186/s12929-017-0387-z
