The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell de...
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration
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Author / Creator
Schoof, Melanie , Launspach, Michael , Holdhof, Dörthe , Nguyen, Lynhda , Engel, Verena , Filser, Severin , Peters, Finn , Immenschuh, Jana , Hellwig, Malte , Niesen, Judith , Mall, Volker , Ertl-Wagner, Birgit , Hagel, Christian , Spohn, Michael , Lutz, Beat , Sedlacik, Jan , Indenbirken, Daniela , Merk, Daniel J. and Schüller, Ulrich
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutations within the
CBP
gene are known to cause Rubinstein-Taybi syndrome (RSTS), a developmental disorder characterized by intellectual disab...
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Full title
The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration
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Author / Creator
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TN_cdi_doaj_primary_oai_doaj_org_article_6ca04c132be94fa7b691ec045f179d0f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ca04c132be94fa7b691ec045f179d0f
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-019-0849-5