Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from l...
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Epigenetic silencing of regulatory genes by aberrant methylation contributes to tumorigenesis. DNA methyltransferase inhibitors (DNMTI) represent promising new drugs for anti-cancer therapies. The DNMTI 5-Azacytidine is effective against myelodysplastic syndrome, but induces switching of latent to lytic Epstein-Barr virus (EBV)
in vitro
and r...
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Full title
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells
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TN_cdi_doaj_primary_oai_doaj_org_article_6ca942d2af8c468c95fd0236aa7254f0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ca942d2af8c468c95fd0236aa7254f0
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-6-3
