Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth
Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oncogenes such as K‐
ras
mediate cellular and metabolic transformation during tumorigenesis. To analyze K‐Ras‐dependent metabolic alterations, we employed
13
C metabolic flux analysis (MFA), non‐targeted tracer fate detection (NTFD) of
15
N‐labeled glutamine, and transcriptomic profiling in mouse fibroblast and human carcinoma cel...
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Oncogenic K‐Ras decouples glucose and glutamine metabolism to support cancer cell growth
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TN_cdi_doaj_primary_oai_doaj_org_article_6ce407a064f447839dcb55b8a31e227a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ce407a064f447839dcb55b8a31e227a
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ISSN
1744-4292
E-ISSN
1744-4292
DOI
10.1038/msb.2011.56
