Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin si...
Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin signalling in migraine
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Migraine is a common complex disorder with a significant polygenic SNP heritability (
h
S
N
P
2
). Here we utilise genome-wide association study (GWAS) summary statistics to study pleiotropy between blood proteins and migraine under the polygenic model. We estimate
h
S
N
P
2
for 4625 blood protein GWASs and ident...
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Full title
Genetic analyses identify pleiotropy and causality for blood proteins and highlight Wnt/β-catenin signalling in migraine
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TN_cdi_doaj_primary_oai_doaj_org_article_6d283772a7494853bc299f0832d1c2e3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d283772a7494853bc299f0832d1c2e3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30184-z
