Mutant huntingtin enhances activation of dendritic Kv4 K + channels in striatal spiny projection neu...
Mutant huntingtin enhances activation of dendritic Kv4 K + channels in striatal spiny projection neurons
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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Huntington's disease (HD) is initially characterized by an inability to suppress unwanted movements, a deficit attributable to impaired synaptic activation of striatal indirect pathway spiny projection neurons (iSPNs). To better understand the mechanisms underlying this deficit, striatal neurons in ex vivo brain slices from mouse genetic models of...
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Mutant huntingtin enhances activation of dendritic Kv4 K + channels in striatal spiny projection neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_6d433a31aa0f4103a04bf72732b8b59c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d433a31aa0f4103a04bf72732b8b59c
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.40818
