Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stre...
Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Adult human pancreatic beta cells are the "gold standard" for studies on diabetes pathogenesis, but their use is limited by insufficient availability and variable quality. An important effort has recently taken place to differentiate beta cells from human induced pluripotent stem cells (iPSCs) and validate their use for diabetes research. We presen...
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Full title
Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
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TN_cdi_doaj_primary_oai_doaj_org_article_6d4d18458ce44a819c6737f90ba938f9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d4d18458ce44a819c6737f90ba938f9
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-019-1523-3
