Ibetazol, a novel inhibitor of importin β1-mediated nuclear import
Ibetazol, a novel inhibitor of importin β1-mediated nuclear import
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Nucleocytoplasmatic transport plays an essential role in eukaryotic cell homeostasis and is mediated by karyopherins. Importin β1 (KPNB1) and its adaptor protein importin α1 (KPNA2) are the best-characterized karyopherins that effect nuclear import. Here, we identify a novel small-molecule inhibitor of the importin β1-mediated nuclear import. We de...
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Ibetazol, a novel inhibitor of importin β1-mediated nuclear import
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TN_cdi_doaj_primary_oai_doaj_org_article_6d5b372d2108496cbb7b665ef0f808a6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d5b372d2108496cbb7b665ef0f808a6
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-07237-8
