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Targeting KRAS: from metabolic regulation to cancer treatment

Targeting KRAS: from metabolic regulation to cancer treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d7a8d38098743909ff8bd8e5bb3b117

Targeting KRAS: from metabolic regulation to cancer treatment

About this item

Full title

Targeting KRAS: from metabolic regulation to cancer treatment

Publisher

England: BioMed Central Ltd

Journal title

Molecular cancer, 2025-01, Vol.24 (1), p.9-21, Article 9

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The Kirsten rat sarcoma viral oncogene homolog (KRAS) protein plays a key pathogenic role in oncogenesis, cancer progression, and metastasis. Numerous studies have explored the role of metabolic alterations in KRAS-driven cancers, providing a scientific rationale for targeting metabolism in cancer treatment. The development of KRAS-specific inhibit...

Alternative Titles

Full title

Targeting KRAS: from metabolic regulation to cancer treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6d7a8d38098743909ff8bd8e5bb3b117

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d7a8d38098743909ff8bd8e5bb3b117

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-024-02216-3

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