22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation...
22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation relative to humanized NSG-SGM3 mice
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundEngraftment efficiency of human immune cell lineages in super immunodeficient mice varies, and numerous strains have been developed to improve reconstitution of humanized immune system mice. NSG-SGM3 and NOG-EXL mice combine severe immunodeficiency with transgenic expression of human myeloid stimulatory cytokines, resulting in improved ex...
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22 Humanized NOG-EXL mice exhibit improved overall survival and less severe myeloid cell activation relative to humanized NSG-SGM3 mice
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TN_cdi_doaj_primary_oai_doaj_org_article_6d8b03048d2f4291923672da843e7972
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d8b03048d2f4291923672da843e7972
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.0022