Engineering IL-10 and rapamycin to bind collagen leads to improved anti fibrotic efficacy in lung an...
Engineering IL-10 and rapamycin to bind collagen leads to improved anti fibrotic efficacy in lung and kidney fibrosis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Fibrotic diseases are involved in 45% of deaths in the United States. In particular, fibrosis of the kidney and lung are major public health concerns due to their high prevalence and lack of existing treatment options. Here, we harness the pathophysiological features of fibrotic diseases, namely leaky vasculature and aberrant extracellular matrix (...
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Engineering IL-10 and rapamycin to bind collagen leads to improved anti fibrotic efficacy in lung and kidney fibrosis
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TN_cdi_doaj_primary_oai_doaj_org_article_6df4443129b347af9e00cebe8c87ed71
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6df4443129b347af9e00cebe8c87ed71
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-025-94073-3
