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Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol-rRNA axis

Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol-rRNA axis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6dfeb262bdb4493db52dc5015c7c3b66

Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol-rRNA axis

About this item

Full title

Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol-rRNA axis

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2022-12, Vol.22 (1), p.1351-1351, Article 1351

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Glioma-initiating cells (GICs) are the source of glioma cells that can self-renew, have pluripotency, and are treatment-resistant, so are the starting point for relapse and eventual death despite multimodality therapy. L-[methyl-
C] methionine PET has observed high accumulation at the time of recurrence, it is important to understand the mechani...

Alternative Titles

Full title

Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol-rRNA axis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6dfeb262bdb4493db52dc5015c7c3b66

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6dfeb262bdb4493db52dc5015c7c3b66

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-022-10280-5

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