In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Our understanding of the spatiotemporal regulation of cardiogenesis is hindered by the difficulties in modeling this complex organ currently by in vitro models. Here we develop a method to generate heart organoids from mouse embryonic stem cell-derived embryoid bodies. Consecutive morphological changes proceed in a self-organizing manner in the pre...
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In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
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TN_cdi_doaj_primary_oai_doaj_org_article_6e0a5c1a58564f4ca225428e30d3056d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e0a5c1a58564f4ca225428e30d3056d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18031-5
