PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade ra...
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy
About this item
Full title
Author / Creator
Fischer, Thomas , Hartmann, Oliver , Reissland, Michaela , Prieto-Garcia, Cristian , Klann, Kevin , Pahor, Nikolett , Schülein-Völk, Christina , Baluapuri, Apoorva , Polat, Bülent , Abazari, Arya , Gerhard-Hartmann, Elena , Kopp, Hans-Georg , Essmann, Frank , Rosenfeldt, Mathias , Münch, Christian , Flentje, Michael and Diefenbacher, Markus E.
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
Despite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN. These tumors are supposed to be more resistant to radiation, chemo- and immunotherapy.
We demonstrate that loss of PTEN led to altered expressio...
Alternative Titles
Full title
PTEN mutant non-small cell lung cancer require ATM to suppress pro-apoptotic signalling and evade radiotherapy
Authors, Artists and Contributors
Author / Creator
Hartmann, Oliver
Reissland, Michaela
Prieto-Garcia, Cristian
Klann, Kevin
Pahor, Nikolett
Schülein-Völk, Christina
Baluapuri, Apoorva
Polat, Bülent
Abazari, Arya
Gerhard-Hartmann, Elena
Kopp, Hans-Georg
Essmann, Frank
Rosenfeldt, Mathias
Münch, Christian
Flentje, Michael
Diefenbacher, Markus E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6e2b77747e884b2d9b01fa05018ce46e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e2b77747e884b2d9b01fa05018ce46e
Other Identifiers
ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-022-00778-7
