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Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e375a589b1f4e66989e48a1fe42c693

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

About this item

Full title

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

Publisher

United States: Elsevier Limited

Journal title

Molecular therapy. Methods & clinical development, 2014-07, Vol.1 (C), p.14030, Article 14030

Language

English

Formats

Publication information

Publisher

United States: Elsevier Limited

More information

Scope and Contents

Contents

Adoptive cell therapy utilizing
expanded polyclonal CD4
CD25
FOXP3
regulatory T cells (Treg) is in use in clinical trials for the treatment of type 1 diabetes and prevention of graft vs host disease in bone marrow transplantation. Here we seek to evaluate this approach in the treatment of inherited protein deficiencies,
hemophilia, w...

Alternative Titles

Full title

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6e375a589b1f4e66989e48a1fe42c693

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e375a589b1f4e66989e48a1fe42c693

Other Identifiers

ISSN

2329-0501

E-ISSN

2329-0501

DOI

10.1038/mtm.2014.30

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