The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal...
The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
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Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
While the mechanisms by which chemical signals control cell fate have been well studied, the impact of mechanical inputs on cell fate decisions is not well understood. Here, using the well-defined system of keratinocyte differentiation in the skin, we examine whether and how direct force transmission to the nucleus regulates epidermal cell fate. Us...
Alternative Titles
Full title
The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
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TN_cdi_doaj_primary_oai_doaj_org_article_6e479b27d684427e9a03b610382df86f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e479b27d684427e9a03b610382df86f
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.58541
