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Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e54e790902d416d9bb11f07312515cd

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Current doctrine is that microvascular inflammation (MVI) triggered by a transplant -recipient antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Here, we show that histological lesions are not mediated by antibodies in approximately half the participants in a cohort of 129 renal recipients with...

Alternative Titles

Full title

Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6e54e790902d416d9bb11f07312515cd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e54e790902d416d9bb11f07312515cd

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13113-5

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