Efficient protein production inspired by how spiders make silk
Efficient protein production inspired by how spiders make silk
About this item
Full title
Author / Creator
Sveriges lantbruksuniversitet , Kronqvist, Nina , Sarr, Médoune , Lindqvist, Anton , Nordling, Kerstin , Otikovs, Martins , Venturi, Luca , Pioselli, Barbara , Purhonen, Pasi , Landreh, Michael , Biverstål, Henrik , Toleikis, Zigmantas , Sjöberg, Lisa , Robinson, Carol V. , Pelizzi, Nicola , Jörnvall, Hans , Hebert, Hans , Jaudzems, Kristaps , Curstedt, Tore , Rising, Anna and Johansson, Jan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Membrane proteins are targets of most available pharmaceuticals, but they are difficult to produce recombinantly, like many other aggregation-prone proteins. Spiders can produce silk proteins at huge concentrations by sequestering their aggregation-prone regions in micellar structures, where the very soluble N-terminal domain (NT) forms the shell....
Alternative Titles
Full title
Efficient protein production inspired by how spiders make silk
Authors, Artists and Contributors
Author / Creator
Kronqvist, Nina
Sarr, Médoune
Lindqvist, Anton
Nordling, Kerstin
Otikovs, Martins
Venturi, Luca
Pioselli, Barbara
Purhonen, Pasi
Landreh, Michael
Biverstål, Henrik
Toleikis, Zigmantas
Sjöberg, Lisa
Robinson, Carol V.
Pelizzi, Nicola
Jörnvall, Hans
Hebert, Hans
Jaudzems, Kristaps
Curstedt, Tore
Rising, Anna
Johansson, Jan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6e88916356bd45a19c0f201d1ebfd6e8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e88916356bd45a19c0f201d1ebfd6e8
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15504
